Amazon Bedrock has launched general availability for OpenAI models, including GPT-5.5, GPT-5.4, and Codex, allowing developers to deploy them in production applications and agents. The models run on Bedrock’s high-performance inference engine, which supports existing AWS commitments and provides reliable, secure performance. GPT-5.5, the most advanced model from OpenAI, is designed to grasp user intent faster and handle multi-step tasks autonomously, excelling in coding, data analysis, and document generation. Both GPT-5.5 and GPT-5.4 are available in the Amazon Bedrock model catalog and can be accessed via the Responses API, with pricing matching OpenAI’s first-party rates. Bedrock’s inference engine includes automated capacity management, durable state capture, and governance controls such as IAM permissions, VPC isolation, KMS encryption, and AWS CloudTrail logging. "At Amgen, we’re focused on applying advanced AI in ways that may help accelerate the delivery of potential new therapies while equipping our teams with advanced tools. OpenAI’s GPT-5.5 and frontier models offer compelling advances in capability, quality, and consistency that matter in a field where the questions are complex and the standards for scientific accuracy and decision quality are exceptionally high. Making these models available on AWS gives us an important new path to explore and scale those capabilities within the responsible AI framework, including, security, governance, and operational frameworks across the enterprise," said Sean Bruich, Senior Vice President, Chief Technology Officer at Amgen. Codex, the OpenAI coding agent, is now available on Amazon Bedrock, with inference routed through Bedrock and supporting data residency requirements. "Autodesk is the technology platform for the people who design and make the world around us. Workflows like building design are highly iterative, requiring precision, coordination, and continuous refinement across teams. With OpenAI models and Codex now generally available on Amazon Bedrock, our teams are evaluating how frontier AI capabilities and AI-powered development tools on scalable, secure AWS infrastructure can help accelerate development workflows and support more informed decision-making for our customers," said Ritesh Bansal, VP of Analytics Data, Agentic AI and AI/ML Platform at Autodesk. *Source: [awsml](https://aws.amazon.com/blogs/machine-learning/openai-models-and-codex-on-amazon-bedrock-are-now-generally-available/)*